Treatment with metallic gold reduces proliferation of inflammatory cells following experimental traumatic brain injury

The authors examine the effect of gold implants in the case of traumatic brain injuries. They injected 25–45 m gold particles into the brain tissue of mice and caused a cryo-lesion (icing) near the injection. Placebo-treated mice received cryo-lesion for control. In the case of gold treatment there were fewer activated microglia (macrophage cells) and significantly more signalling proteins that regulate cell growth (growth factors); also cell proliferation occurred. The authors consider this to be confirmation of the anti-inflammatory effect of bio-released gold ions demonstrated by other researchers and conclude that metallic gold increases growth factor expression and production of nervous system cells.

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